Preeclampsia is defined as the combination of high blood pressure (hypertension), swelling (edema), and
protein in the urine (albuminuria, proteinuria) developing after the 20th week of pregnancy.1 Preeclampsia ranges in severity from mild to severe; the mild form is
sometimes called proteinuric pregnancy-induced hypertension2 or
proteinuric gestational hypertension.3
Women with even mild preeclampsia must be monitored carefully by a healthcare professional.
Hospitalization may be necessary to enable close observation.4
The cause of preeclampsia is unknown, although several factors have been shown to contribute.5, 6 Preeclampsia is more common in women during their first pregnancy,7 as well as in women who are obese,8, 9 who have diabetes,10 or who have
gestational hypertension.11, 12, 13 Women who have had preeclampsia during a previous pregnancy are also
at increased risk.14 Preeclampsia has also been associated with calcium
deficiencies,15antioxidant
deficiencies,16, 17, 18 older maternal
age,19 and job stress.20, 21, 22