Also indexed as:Beta Hydroxy-Beta-Methylbutyrate
How Much Is Usually Taken by Dieters?
Biochemical and animal research shows HMB has a role in protein synthesis and might improve muscle growth and overall body composition as a supplement. However, double-blind human research suggests that HMB may only be effective when combined with an exercise program in people who are not already highly trained athletes. Double-blind trials found no effect of 3 to 6 grams per day HMB on body weight, body fat, or overall body composition in weight-training football players or other trained athletes.1, 2, 3, 4, 5 However, one double-blind study found that 3 grams per day HMB increased the amount of body fat lost by 70-year old adults who were participating in a strength-training program for the first time.6 A double-blind study of young men with no strength-training experience reported greater improvements in muscle mass (but not in percentage body fat) when HMB was used in the amount of 17 mg per pound of body weight.7 However, another group of men in the same study given twice as much HMB did not experience any changes in body composition.
At the time of writing, there were no well-known side effects caused by this supplement.
Interactions with Supplements, Foods, & Other Compounds
At the time of writing, there were no well-known supplement or food interactions with this supplement.
Interactions with Medicines
As of the last update, we found no reported interactions between this supplement and medicines. It is possible that unknown interactions exist. If you take medication, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.
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The information presented in Aisle7 is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires June 2014.